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My aunt was diagnosed with Addison’s disease several years ago. The disease started unnoticeably and developed rather slowly. The whole family paid no attention to the first symptoms: tiredness, loss of appetite, low blood pressure. It all seemed to me separate symptoms of dietary changes, lack of sleep, etc. then when my aunt started feeling sudden pain in her back and her hands started shaking my dad (her brother) persuaded her to have some medical tests and screenings. It all took about 2 months before she was finally diagnosed with adrenal insufficiency and initial stage of Addison’s disease. The doctor explained that if not treated professionally and on time the disease could be life-threatening. He put my aunt on several different medications but they caused unacceptable side effects – vomiting after every food intake, insomnia, sometimes her blood pressure could suddenly rise high and she had frequent bleedings at the nose. Then she was put on Florinef and the situation changed completely. The medication is a corticosteroid aimed to treat adrenal insufficiency and it is just perfect for its purpose. My aunts test results are much better with Florinef. Besides it causes practically no side effects. Just slight dizziness in the morning, which disappears when she eats something. We are all happy to see her condition improving and we hope the disease won’t develop any further. And of course we are all very impressed with Florinef. Excellent drug for adrenal insufficiency.
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My younger daughter was prescribed with Florinef three months ago, may be this period of time is not sufficient to judge about the efficiency of a corticosteroid but I am so pleased with the way Florinef works that I decided to share my opinion with others. Our diagnosis is congenital adrenal hyperplasia, as our doctor – pediatric endocrinologist – explained it means that my daughter’s adrenal glands don’t produce enough cortisol for her body. She was diagnosed at an early age, when her height and weight just slightly differed from the norm. The doctor prescribed Florinef to boost the levels of deficient hormones in my baby. Since the time we started on Florinef we undergo regular tests to monitor her condition and according to the test results the medication works perfectly well. There is almost no threat for her normal growth. The prognosis is very optimistic. With the help of Florinef my daughter will be able to grow normally, the only condition is careful dosage of the medication and regular monitoring by her doctor. We are very happy as we were really scared by the diagnosis. What is also very important for me is that the medication produces almost no side effects. That would be horrible to see your little child suffer not being able to help. So, I?m 100% satisfied with the effectiveness of Florinef and I hope it will continue to work this way.
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Superinfection was defined as a new infection occurring 48 hours or more after the initiation of a study drug.
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In 20 patients with positive adrenal antibodies and various degrees of adrenal hypofunction, monitored for 5 years, six patients with subclinical adrenal failure, whose antibodies spontaneously disappeared with time, showed an improvement in adrenal function.
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If you have been diagnosed with adrenal insufficiency, you should wear a medical identification bracelet or necklace at all times should an emergency develop.
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UK Trial (ref: Lancet 1999, 353, 455 – 458), using a lower dose of hydrocortisone, also reported some degree of improvement in fatigue, symptoms, and disability level.
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